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Eliminating primer dimers and improving SNP detection using self-avoiding molecular recognition systems

Despite its widespread value to molecular biology, the polymerase chain reaction (PCR) encounters modes that unproductively consume PCR resources and prevent clean signals, especially when high sensitivity, high SNP discrimination, and high multiplexing are sought. Here, we show how “self-avoiding m...

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Detalles Bibliográficos
Autores principales: Yang, Zunyi, Le, Jennifer T, Hutter, Daniel, Bradley, Kevin M, Overton, Benjamin R, McLendon, Chris, Benner, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200914/
https://www.ncbi.nlm.nih.gov/pubmed/32395633
http://dx.doi.org/10.1093/biomethods/bpaa004