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Eliminating primer dimers and improving SNP detection using self-avoiding molecular recognition systems
Despite its widespread value to molecular biology, the polymerase chain reaction (PCR) encounters modes that unproductively consume PCR resources and prevent clean signals, especially when high sensitivity, high SNP discrimination, and high multiplexing are sought. Here, we show how “self-avoiding m...
Autores principales: | Yang, Zunyi, Le, Jennifer T, Hutter, Daniel, Bradley, Kevin M, Overton, Benjamin R, McLendon, Chris, Benner, Steven A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200914/ https://www.ncbi.nlm.nih.gov/pubmed/32395633 http://dx.doi.org/10.1093/biomethods/bpaa004 |
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