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TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

BACKGROUND & AIMS: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown. Recently, we developed an HDV replication mouse model in which, for the first time, liver damage was detected. METHODS: HDV and HB...

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Detalles Bibliográficos
Autores principales: Usai, Carla, Maestro, Sheila, Camps, Gracian, Olague, Cristina, Suárez-Amaran, Lester, Vales, Africa, Aragon, Tomas, Hommel, Mirja, Aldabe, Rafael, Gonzalez-Aseguinolaza, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200939/
https://www.ncbi.nlm.nih.gov/pubmed/32382723
http://dx.doi.org/10.1016/j.jhepr.2020.100098