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TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection
BACKGROUND & AIMS: HDV infection induces the most severe form of human viral hepatitis. However, the specific reasons for the severity of the disease remain unknown. Recently, we developed an HDV replication mouse model in which, for the first time, liver damage was detected. METHODS: HDV and HB...
Autores principales: | Usai, Carla, Maestro, Sheila, Camps, Gracian, Olague, Cristina, Suárez-Amaran, Lester, Vales, Africa, Aragon, Tomas, Hommel, Mirja, Aldabe, Rafael, Gonzalez-Aseguinolaza, Gloria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200939/ https://www.ncbi.nlm.nih.gov/pubmed/32382723 http://dx.doi.org/10.1016/j.jhepr.2020.100098 |
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