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Enzyme-linked oligonucleotide hybridization assay for direct oligo measurement in blood

Small oligonucleotides (oligos) are increasingly being utilized as diagnostics or treatments for disease. An impediment to broader use is the ability to readily measure oligos in biological fluids. Here, we describe a very straightforward assay with detection in the sub-picomole range that does not...

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Detalles Bibliográficos
Autores principales: Lorenson, Mary Y, Chen, Kuan-Hui Ethan, Walker, Ameae M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200967/
https://www.ncbi.nlm.nih.gov/pubmed/32395619
http://dx.doi.org/10.1093/biomethods/bpy014