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Enzyme-linked oligonucleotide hybridization assay for direct oligo measurement in blood
Small oligonucleotides (oligos) are increasingly being utilized as diagnostics or treatments for disease. An impediment to broader use is the ability to readily measure oligos in biological fluids. Here, we describe a very straightforward assay with detection in the sub-picomole range that does not...
Autores principales: | Lorenson, Mary Y, Chen, Kuan-Hui Ethan, Walker, Ameae M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200967/ https://www.ncbi.nlm.nih.gov/pubmed/32395619 http://dx.doi.org/10.1093/biomethods/bpy014 |
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