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Characterisation of unessential genes required for survival under conditions of DNA stress

BACKGROUND: Genomic instability is a hallmark of cancer. Cancer progression depends on the development and amplification of mutations that alter the cellular response to threats to the genome. This can lead to DNA replication stress and the potential loss of genetic integrity of the newly formed cel...

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Detalles Bibliográficos
Autores principales: Ahmed Ezzat, Hassan, Price, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201005/
https://www.ncbi.nlm.nih.gov/pubmed/32372157
http://dx.doi.org/10.1186/s43141-020-00025-x