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Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126

Heat shock protein A12B (HSPA12B) is predominately expressed in endothelial cells (ECs) and has been reported to protect against cardiac dysfunction from endotoxemia or myocardial infarction. This study investigated the mechanisms by which endothelial HSPA12B protects polymicrobial sepsis–induced ca...

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Detalles Bibliográficos
Autores principales: Zhang, Xia, Wang, Xiaohui, Fan, Min, Tu, Fei, Yang, Kun, Ha, Tuanzhu, Liu, Li, Kalbfleisch, John, Williams, David, Li, Chuanfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201039/
https://www.ncbi.nlm.nih.gov/pubmed/32411123
http://dx.doi.org/10.3389/fimmu.2020.00566