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Ethanol Extract of Brucea javanica Seed Inhibit Triple-Negative Breast Cancer by Restraining Autophagy via PI3K/Akt/mTOR Pathway

Triple-negative breast cancer (TNBC) is an aggressive disease with worst prognosis than other subtypes of breast cancer. Owing to the lack of hormone receptors and HER2 expression on TNBC cells, patients do not have targeted therapy options available with other breast cancer subtypes. Extensive effo...

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Detalles Bibliográficos
Autores principales: Chen, Xiaohong, Li, Shuang, Li, Dan, Li, Muxia, Su, Ziren, Lai, Xiaoping, Zhou, Changlin, Chen, Shaodan, Li, Shunxian, Yang, Xiaobing, Su, Jiyan, Zhang, Yunjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201043/
https://www.ncbi.nlm.nih.gov/pubmed/32411003
http://dx.doi.org/10.3389/fphar.2020.00606