3′-UTR Shortening Contributes to Subtype-Specific Cancer Growth by Breaking Stable ceRNA Crosstalk of Housekeeping Genes

Shortening of 3′UTRs (3′US) through alternative polyadenylation is a post-transcriptional mechanism that regulates the expression of hundreds of genes in human cancers. In breast cancer, different subtypes of tumor samples, such as estrogen receptor positive and negative (ER+ and ER–), are character...

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Detalles Bibliográficos
Autores principales: Fan, Zhenjiang, Kim, Soyeon, Bai, Yulong, Diergaarde, Brenda, Park, Hyun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201092/
https://www.ncbi.nlm.nih.gov/pubmed/32411683
http://dx.doi.org/10.3389/fbioe.2020.00334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201092/
https://www.ncbi.nlm.nih.gov/pubmed/32411683
http://dx.doi.org/10.3389/fbioe.2020.00334

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