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3′-UTR Shortening Contributes to Subtype-Specific Cancer Growth by Breaking Stable ceRNA Crosstalk of Housekeeping Genes
Shortening of 3′UTRs (3′US) through alternative polyadenylation is a post-transcriptional mechanism that regulates the expression of hundreds of genes in human cancers. In breast cancer, different subtypes of tumor samples, such as estrogen receptor positive and negative (ER+ and ER–), are character...
Autores principales: | Fan, Zhenjiang, Kim, Soyeon, Bai, Yulong, Diergaarde, Brenda, Park, Hyun Jung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201092/ https://www.ncbi.nlm.nih.gov/pubmed/32411683 http://dx.doi.org/10.3389/fbioe.2020.00334 |
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