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Computational Modeling of Human Mesenchymal Stromal Cell Proliferation and Extra-Cellular Matrix Production in 3D Porous Scaffolds in a Perfusion Bioreactor: The Effect of Growth Factors

Stem cell expansion on 3D porous scaffolds cultured in bioreactor systems has been shown to be beneficial for maintenance of the original cell functionality in tissue engineering strategies (TE). However, the production of extracellular matrix (ECM) makes harvesting the progenitor cell population fr...

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Detalles Bibliográficos
Autores principales: Mehrian, Mohammad, Lambrechts, Toon, Papantoniou, Ioannis, Geris, Liesbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201129/
https://www.ncbi.nlm.nih.gov/pubmed/32411692
http://dx.doi.org/10.3389/fbioe.2020.00376