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FNDC3B, Targeted by miR-125a-5p and miR-217, Promotes the Proliferation and Invasion of Colorectal Cancer Cells via PI3K/mTOR Signaling

BACKGROUND: Fibronectin type III domain containing 3B (FNDC3B) acts as an oncogene in various cancers, and abnormal expression of FNDC3B has been found in colorectal cancer (CRC). Our study aimed to illustrate the role of FNDC3B in CRC development. METHODS: Through RT-qPCR and western blotting assay...

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Detalles Bibliográficos
Autores principales: Li, Yilong, Yang, Jie, Wang, Hengyang, Qiao, Wei, Guo, Yongfeng, Zhang, Shengtao, Guo, Yajuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201223/
https://www.ncbi.nlm.nih.gov/pubmed/32431508
http://dx.doi.org/10.2147/OTT.S226520