Cargando…

Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non‐Small Cell Lung Cancer

The evolutionary dynamics of tumor‐associated neoantigens carry information about drug sensitivity and resistance to the immune checkpoint blockade (ICB). However, the spectrum of somatic mutations is highly heterogeneous among patients, making it difficult to track neoantigens by circulating tumor...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Qingzhu, Chiu, Luting, Wu, Shuangxiu, Bai, Jian, Peng, Lina, Zheng, Linpeng, Zang, Rui, Li, Xueqin, Yuan, Bibo, Gao, Yixing, Wu, Dingyong, Li, Xiaohong, Wu, Lin, Sun, Jianguo, He, Ji, Robinson, Bruce W. S., Zhu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201246/
https://www.ncbi.nlm.nih.gov/pubmed/32382482
http://dx.doi.org/10.1002/advs.201903410