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Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non‐Small Cell Lung Cancer
The evolutionary dynamics of tumor‐associated neoantigens carry information about drug sensitivity and resistance to the immune checkpoint blockade (ICB). However, the spectrum of somatic mutations is highly heterogeneous among patients, making it difficult to track neoantigens by circulating tumor...
Autores principales: | Jia, Qingzhu, Chiu, Luting, Wu, Shuangxiu, Bai, Jian, Peng, Lina, Zheng, Linpeng, Zang, Rui, Li, Xueqin, Yuan, Bibo, Gao, Yixing, Wu, Dingyong, Li, Xiaohong, Wu, Lin, Sun, Jianguo, He, Ji, Robinson, Bruce W. S., Zhu, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201246/ https://www.ncbi.nlm.nih.gov/pubmed/32382482 http://dx.doi.org/10.1002/advs.201903410 |
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