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Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures

Malaria is a devastating disease caused by a protozoan parasite. It affects over 300 million individuals and results in over 400 000 deaths annually, most of whom are young children under the age of five. Hexokinase, the first enzyme in glucose metabolism, plays an important role in the infection pr...

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Detalles Bibliográficos
Autores principales: Srivastava, Shanti Swaroop, Darling, Joseph E., Suryadi, Jimmy, Morris, James C., Drew, Mark E., Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201273/
https://www.ncbi.nlm.nih.gov/pubmed/32431829
http://dx.doi.org/10.1107/S2052252520002456