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Hypothesis for a mechanism of beam-induced motion in cryo-electron microscopy
Estimates of heat-transfer rates during plunge-cooling and the patterns of ice observed in cryo-EM samples indicate that the grid bars cool much more slowly than do the support foil and sample near the middle of the grid openings. The resulting transient temperature differences generate transient te...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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International Union of Crystallography
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201280/ https://www.ncbi.nlm.nih.gov/pubmed/32431825 http://dx.doi.org/10.1107/S2052252520002560 |