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Hypothesis for a mechanism of beam-induced motion in cryo-electron microscopy

Estimates of heat-transfer rates during plunge-cooling and the patterns of ice observed in cryo-EM samples indicate that the grid bars cool much more slowly than do the support foil and sample near the middle of the grid openings. The resulting transient temperature differences generate transient te...

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Detalles Bibliográficos
Autor principal: Thorne, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201280/
https://www.ncbi.nlm.nih.gov/pubmed/32431825
http://dx.doi.org/10.1107/S2052252520002560