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High-resolution cryo-EM reconstructions in the presence of substantial aberrations

Here, an analysis is performed of how uncorrected antisymmetric aberrations, such as coma and trefoil, affect cryo-EM single-particle reconstruction (SPR) results, and an analytical formula quantifying information loss owing to their presence is inferred that explains why Fourier-shell coefficient-b...

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Detalles Bibliográficos
Autores principales: Bromberg, Raquel, Guo, Yirui, Borek, Dominika, Otwinowski, Zbyszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201289/
https://www.ncbi.nlm.nih.gov/pubmed/32431828
http://dx.doi.org/10.1107/S2052252520002444