CTLA4-Ig Abatacept Ameliorates Proteinuria by Regulating Circulating Treg/IL-17 in Adriamycin-Induced Nephropathy Rats

OBJECTIVE: This study is aimed at investigating the efficacy of CTLA4-Ig abatacept in normalizing proteinuria and its possible mechanism in adriamycin-induced nephropathy (AIN) rats. METHODS: A total of 32 healthy male Sprague-Dawley rats were randomly divided into a normal group, an AIN group, an a...

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Detalles Bibliográficos
Autores principales: Shuai, Lanjun, Cheng, Qia, Shen, Tian, Yi, Zhuwen, Wu, Xiaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201454/
https://www.ncbi.nlm.nih.gov/pubmed/32420329
http://dx.doi.org/10.1155/2020/2347827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201454/
https://www.ncbi.nlm.nih.gov/pubmed/32420329
http://dx.doi.org/10.1155/2020/2347827

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