High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis

Diabetic retinopathy (DR) is one of the hallmark complications of diabetes and a leading cause of vision loss in adults. Retinal pericyte death seems to be a prominent feature in the onset of DR. Pyroptosis is an inflammatory form of programmed cell death, defined as being caspase-gasdermin-D (GSDMD...

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Detalles Bibliográficos
Autores principales: Gan, Jinhua, Huang, Maomao, Lan, Genyin, Liu, Li, Xu, Fangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201508/
https://www.ncbi.nlm.nih.gov/pubmed/32420343
http://dx.doi.org/10.1155/2020/4510628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201508/
https://www.ncbi.nlm.nih.gov/pubmed/32420343
http://dx.doi.org/10.1155/2020/4510628

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