Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells

Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease characterized by progressive degeneration of motor neurons in the central nervous system. Prostaglandin E2 (PGE2) plays a pivotal role in the degeneration of motor neurons in human and transgenic models of ALS. We have shown p...

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Detalles Bibliográficos
Autores principales: Kosuge, Yasuhiro, Nango, Hiroshi, Kasai, Hiroki, Yanagi, Takuya, Mawatari, Takayuki, Nishiyama, Kenta, Miyagishi, Hiroko, Ishige, Kumiko, Ito, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201578/
https://www.ncbi.nlm.nih.gov/pubmed/32411331
http://dx.doi.org/10.1155/2020/6101838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201578/
https://www.ncbi.nlm.nih.gov/pubmed/32411331
http://dx.doi.org/10.1155/2020/6101838

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