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Generation of Cellular Reactive Oxygen Species by Activation of the EP2 Receptor Contributes to Prostaglandin E2-Induced Cytotoxicity in Motor Neuron-Like NSC-34 Cells

Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease characterized by progressive degeneration of motor neurons in the central nervous system. Prostaglandin E2 (PGE2) plays a pivotal role in the degeneration of motor neurons in human and transgenic models of ALS. We have shown p...

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Detalles Bibliográficos
Autores principales:	Kosuge, Yasuhiro, Nango, Hiroshi, Kasai, Hiroki, Yanagi, Takuya, Mawatari, Takayuki, Nishiyama, Kenta, Miyagishi, Hiroko, Ishige, Kumiko, Ito, Yoshihisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201578/ https://www.ncbi.nlm.nih.gov/pubmed/32411331 http://dx.doi.org/10.1155/2020/6101838

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