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Effect of Quercetin on PC12 Alzheimer's Disease Cell Model Induced by Aβ(25-35) and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway

OBJECTIVE: This study is aimed at studying the effect of quercetin on the Alzheimer disease cell model induced by Aβ(25-35) in PC12 cells and its mechanism of action. METHODS: The AD cell model was established by Aβ(25-35). Quercetin was used at different concentrations (0, 10, 20, 40, and 80 μmol/L...

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Detalles Bibliográficos
Autores principales: Yu, Xinjun, Li, Yicai, Mu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201675/
https://www.ncbi.nlm.nih.gov/pubmed/32420373
http://dx.doi.org/10.1155/2020/8210578