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Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model

BACKGROUND: It is widely hoped that personal cancer vaccines will extend the number of patients benefiting from checkpoint and other immunotherapies. However, it is clear creating such vaccines will be challenging. It requires obtaining and sequencing tumor DNA/RNA, predicting potentially immunogeni...

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Detalles Bibliográficos
Autores principales: Peterson, Milene, Murphy, Sierra Nicole, Lainson, John, Zhang, Jian, Shen, Luhui, Diehnelt, Chris W., Johnston, Stephen Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201681/
https://www.ncbi.nlm.nih.gov/pubmed/32370785
http://dx.doi.org/10.1186/s12865-020-00350-3