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Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model
BACKGROUND: It is widely hoped that personal cancer vaccines will extend the number of patients benefiting from checkpoint and other immunotherapies. However, it is clear creating such vaccines will be challenging. It requires obtaining and sequencing tumor DNA/RNA, predicting potentially immunogeni...
Autores principales: | Peterson, Milene, Murphy, Sierra Nicole, Lainson, John, Zhang, Jian, Shen, Luhui, Diehnelt, Chris W., Johnston, Stephen Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201681/ https://www.ncbi.nlm.nih.gov/pubmed/32370785 http://dx.doi.org/10.1186/s12865-020-00350-3 |
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