Selective profiling of N- and C-terminal nucleotide-binding sites in a TRPM2 channel

Transient receptor potential melastatin 2 (TRPM2) is a homotetrameric Ca(2+)-permeable cation channel important for the immune response, body temperature regulation, and insulin secretion, and is activated by cytosolic Ca(2+) and ADP ribose (ADPR). ADPR binds to two distinct locations, formed by lar...

Descripción completa

Detalles Bibliográficos
Autores principales: Tóth, Balázs, Iordanov, Iordan, Csanády, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201885/
https://www.ncbi.nlm.nih.gov/pubmed/32211872
http://dx.doi.org/10.1085/jgp.201912533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201885/
https://www.ncbi.nlm.nih.gov/pubmed/32211872
http://dx.doi.org/10.1085/jgp.201912533

Ejemplares similares