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Engineering an enhanced voltage-sensing phosphatase

Voltage-sensing phosphatases (VSP) consist of a membrane-spanning voltage sensor domain and a cytoplasmic region that has enzymatic activity toward phosphoinositides (PIs). VSP enzyme activity is regulated by membrane potential, and its activation leads to rapid and reversible alteration of cellular...

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Detalles Bibliográficos
Autores principales: Kawanabe, Akira, Mizutani, Natsuki, Polat, Onur K., Yonezawa, Tomoko, Kawai, Takafumi, Mori, Masayuki X., Okamura, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201886/
https://www.ncbi.nlm.nih.gov/pubmed/32167537
http://dx.doi.org/10.1085/jgp.201912491