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Silencing Signal Transducer and Activator of Transcription 3 (STAT3) and Use of Anti-Programmed Cell Death-Ligand 1 (PD-L1) Antibody Induces Immune Response and Anti-Tumor Activity

BACKGROUND: The treatment of cancer is still unable to meet the needs of patients and remains a huge challenge. This study investigated the immune response and anti-cancer effect of silencing STAT3 combined with the use of anti-PD-L1 antibody. MATERIAL/METHODS: Transfected CT26.WT cells were used to...

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Detalles Bibliográficos
Autores principales: Wang, Jiaxing, Huang, Fakun, Jiang, Caiyun, Chi, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201895/
https://www.ncbi.nlm.nih.gov/pubmed/32343679
http://dx.doi.org/10.12659/MSM.915854