Apoptosis Activation in Thyroid Cancer Cells by Jatrorrhizine-Platinum(II) Complex via Downregulation of PI3K/AKT/Mammalian Target of Rapamycin (mTOR) Pathway

BACKGROUND: Thyroid cancer, which is the most common endocrine cancer, has shown a drastic increase in incidence globally over the past decade. The present study investigated the thyroid cancer-inhibitory potential of jatrorrhizine-platinum(II) complex (JR-P(II) in vitro and in vivo. MATERIAL/METHOD...

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Detalles Bibliográficos
Autores principales: Lu, KeBin, Wei, Wenjun, Hu, Jiaqian, Wen, Duo, Ma, Ben, Liu, Wanlin, Wang, Yu, Lu, Zhongwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201896/
https://www.ncbi.nlm.nih.gov/pubmed/32341329
http://dx.doi.org/10.12659/MSM.922518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201896/
https://www.ncbi.nlm.nih.gov/pubmed/32341329
http://dx.doi.org/10.12659/MSM.922518

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