USP22 controls iNKT immunity through MED1 suppression of histone H2A monoubiquitination

The ubiquitin pathway has been shown to regulate iNKT cell immunity, but the deubiquitinase involved in this process has not been identified. Herein we found that ubiquitin-specific peptidase 22 (USP22) is highly expressed in iNKT cells during their early developmental stage 1. USP22 deficiency bloc...

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Detalles Bibliográficos
Autores principales: Zhang, Yana, Wang, Yajun, Gao, Beixue, Sun, Yueqi, Cao, Liang, Genardi, Samantha M., Wang, Chyung-Ru, Li, HuaBin, Sun, Zhaolin, Yang, Yanjie, Fang, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201925/
https://www.ncbi.nlm.nih.gov/pubmed/32069354
http://dx.doi.org/10.1084/jem.20182218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201925/
https://www.ncbi.nlm.nih.gov/pubmed/32069354
http://dx.doi.org/10.1084/jem.20182218

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