IL-21 is a broad negative regulator of IgE class switch recombination in mouse and human B cells

IgE antibodies may elicit potent allergic reactions, and their production is tightly controlled. The tendency to generate IgE has been thought to reflect the balance between type 1 and type 2 cytokines, with the latter promoting IgE. Here, we reevaluated this paradigm by a direct cellular analysis,...

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Detalles Bibliográficos
Autores principales: Yang, Zhiyong, Wu, Chung-An M., Targ, Sasha, Allen, Christopher D.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201927/
https://www.ncbi.nlm.nih.gov/pubmed/32130409
http://dx.doi.org/10.1084/jem.20190472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201927/
https://www.ncbi.nlm.nih.gov/pubmed/32130409
http://dx.doi.org/10.1084/jem.20190472

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