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SKN-1 Is a Negative Regulator of DAF-16 and Somatic Stress Resistance in Caenorhabditis elegans

The transcription factor SKN-1, the C. elegans ortholog of mammalian Nrf protein, is a well-known longevity factor, and its activation is observed in several long-lived models. SKN-1 also plays essential roles in xenobiotic and oxidative stress responses. Here, we report deleterious functions of SKN...

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Detalles Bibliográficos
Autores principales: Deng, Jianhui, Dai, Yuxi, Tang, Haiqing, Pang, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202003/
https://www.ncbi.nlm.nih.gov/pubmed/32161088
http://dx.doi.org/10.1534/g3.120.401203