Restriction Enzyme Based Enriched L1Hs Sequencing (REBELseq): A Scalable Technique for Detection of Ta Subfamily L1Hs in the Human Genome

Long interspersed element-1 retrotransposons (LINE-1 or L1) are ∼6 kb mobile DNA elements implicated in the origins of many Mendelian and complex diseases. The actively retrotransposing L1s are mostly limited to the L1 human specific (L1Hs) transcriptional active (Ta) subfamily. In this manuscript,...

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Detalles Bibliográficos
Autores principales: Reiner, Benjamin C., Doyle, Glenn A., Weller, Andrew E., Levinson, Rachel N., Namoglu, Esin, Pigeon, Alicia, Perea, Emilie Dávila, Weickert, Cynthia Shannon, Turecki, Gustavo, Mash, Deborah C., Crist, Richard C., Berrettini, Wade H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202019/
https://www.ncbi.nlm.nih.gov/pubmed/32132168
http://dx.doi.org/10.1534/g3.119.400613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202019/
https://www.ncbi.nlm.nih.gov/pubmed/32132168
http://dx.doi.org/10.1534/g3.119.400613

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