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Synergistic factors control kinase–phosphatase organization in B-cells engaged with supported bilayers

B-cells become activated by ligands with varying valency and mode of presentation to the B-cell receptor (BCR). We previously demonstrated that clustering the immunoglobulin M (IgM) isotype of BCR with an artificial soluble cross-linker stabilized an ordered phase-like domain that enriched kinases a...

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Detalles Bibliográficos
Autores principales: Núñez, Marcos Francisco, Wisser, Kathleen, Veatch, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202075/
https://www.ncbi.nlm.nih.gov/pubmed/31877064
http://dx.doi.org/10.1091/mbc.E19-09-0507