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Synergistic factors control kinase–phosphatase organization in B-cells engaged with supported bilayers
B-cells become activated by ligands with varying valency and mode of presentation to the B-cell receptor (BCR). We previously demonstrated that clustering the immunoglobulin M (IgM) isotype of BCR with an artificial soluble cross-linker stabilized an ordered phase-like domain that enriched kinases a...
Autores principales: | Núñez, Marcos Francisco, Wisser, Kathleen, Veatch, Sarah L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202075/ https://www.ncbi.nlm.nih.gov/pubmed/31877064 http://dx.doi.org/10.1091/mbc.E19-09-0507 |
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