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Multisite EGFR phosphorylation is regulated by adaptor protein abundances and dimer lifetimes
Differential epidermal growth factor receptor (EGFR) phosphorylation is thought to couple receptor activation to distinct signaling pathways. However, the molecular mechanisms responsible for biased signaling are unresolved due to a lack of insight into the phosphorylation patterns of full-length EG...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202077/ https://www.ncbi.nlm.nih.gov/pubmed/31913761 http://dx.doi.org/10.1091/mbc.E19-09-0548 |