High‐grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF‐1

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundance of stroma. Multiple molecular classification efforts have identified a mesenchymal tumor subtype that is consistently characterized by high‐grade growth and poor clinical outcome. The relation between PDAC stroma and tumor subt...

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Detalles Bibliográficos
Autores principales: Steins, Anne, van Mackelenbergh, Madelaine G, van der Zalm, Amber P, Klaassen, Remy, Serrels, Bryan, Goris, Sandrine G, Kocher, Hemant M, Waasdorp, Cynthia, de Jong, Joan H, Tekin, Cansu, Besselink, Marc G, Busch, Olivier R, van de Vijver, Marc J, Verheij, Joanne, Dijk, Frederike, van Tienhoven, Geertjan, Wilmink, Johanna W, Medema, Jan Paul, van Laarhoven, Hanneke WM, Bijlsma, Maarten F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202203/
https://www.ncbi.nlm.nih.gov/pubmed/32173982
http://dx.doi.org/10.15252/embr.201948780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202203/
https://www.ncbi.nlm.nih.gov/pubmed/32173982
http://dx.doi.org/10.15252/embr.201948780

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