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Structure of RyR1 in native membranes

Ryanodine receptor 1 (RyR1) mediates excitation–contraction coupling by releasing Ca(2+) from sarcoplasmic reticulum (SR) to the cytoplasm of skeletal muscle cells. RyR1 activation is regulated by several proteins from both the cytoplasm and lumen of the SR. Here, we report the structure of RyR1 fro...

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Detalles Bibliográficos
Autores principales: Chen, Wenbo, Kudryashev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202208/
https://www.ncbi.nlm.nih.gov/pubmed/32147968
http://dx.doi.org/10.15252/embr.201949891