Gene silencing of indoleamine 2,3-dioxygenase 1 inhibits lung cancer growth by suppressing T-cell exhaustion

Indoleamine 2,3-dioxygenase 1 (IDO1), which degrades the essential amino acid tryptophan, exerts immunosuppressive functions and serves a crucial role in multiple types tumor progression, including non-small-cell lung cancer (NSCLC) and melanoma. Recent studies have reported that T-cell exhaustion i...

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Detalles Bibliográficos
Autores principales: Shang, Ke, Wang, Zhigang, Hu, Yinying, Huang, Yanqin, Yuan, Keng, Yu, Yanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202272/
https://www.ncbi.nlm.nih.gov/pubmed/32382333
http://dx.doi.org/10.3892/ol.2020.11477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202272/
https://www.ncbi.nlm.nih.gov/pubmed/32382333
http://dx.doi.org/10.3892/ol.2020.11477

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