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LncRNA Sox2OT-V7 promotes doxorubicin-induced autophagy and chemoresistance in osteosarcoma via tumor-suppressive miR-142/miR-22

Doxorubicin (Dox) is one of the most commonly used chemotherapeutic drugs for osteosarcoma (OS) treatment. In the present study, we attempted to investigate the mechanism by which Sox2OT-V7 dysregulation affects Dox chemoresistance to provide a novel experimental basis for developing neoadjuvant the...

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Detalles Bibliográficos
Autores principales: Zhu, Kewei, Yuan, Yang, Wen, Jie, Chen, Ding, Zhu, Weihong, Ouyang, Zhengxiao, Wang, Wanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202483/
https://www.ncbi.nlm.nih.gov/pubmed/32302291
http://dx.doi.org/10.18632/aging.103004