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Long non-coding RNA ANRIL alleviates H(2)O(2)-induced injury by up-regulating microRNA-21 in human lens epithelial cells

The accurate role of ANRIL in cataract is poorly understood. We aimed to reveal the effects of ANRIL on H(2)O(2)-treated HLECs, SRA01/04, as well as the regulatory mechanisms. Oxidative stress model of HLECs was induced by H(2)O(2). Cell injury was evaluated according to cell proliferation, apoptosi...

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Detalles Bibliográficos
Autores principales: Du, Shanshan, Shao, Jingzhi, Qi, Ying, Liu, Xuhui, Liu, Jingjing, Zhang, Fengyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202488/
https://www.ncbi.nlm.nih.gov/pubmed/32310822
http://dx.doi.org/10.18632/aging.102800