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PP2A subunit PPP2R2C is downregulated in the brains of Alzheimer’s transgenic mice
Targeting of PP2A suggests a close link to tau-related cognitive and functional declines. However, little is known about how the expression of PP2A subunits and PP2A activity are dysregulated in the course of AD, precluding any specific targeting strategy for restoring PP2A in AD patients. Although...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202491/ https://www.ncbi.nlm.nih.gov/pubmed/32291379 http://dx.doi.org/10.18632/aging.103048 |