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Protective effects of autophagy and NFE2L2 on reactive oxygen species-induced pyroptosis of human nucleus pulposus cells

Intervertebral disc degeneration (IDD) is characterized by the decrease of nucleus pulposus cells (NPCs). With the increase of the degree of degeneration, the reactive oxygen species (ROS) in nucleus pulposus tissue increases. Pyroptosis is a newly discovered form of cell death and its relationship...

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Detalles Bibliográficos
Autores principales: Bai, Zhibiao, Liu, Wei, He, Danshuang, Wang, Yiyang, Yi, Weiwei, Luo, Changqi, Shen, Jieliang, Hu, Zhenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202523/
https://www.ncbi.nlm.nih.gov/pubmed/32320383
http://dx.doi.org/10.18632/aging.103109