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Diabetes-induced glucolipotoxicity impairs wound healing ability of adipose-derived stem cells-through the miR-1248/CITED2/HIF-1α pathway

Despite being an attractive cell type for mesenchymal stem cell (MSC) transplantation therapy for wound healing, human adipose-derived stem cells (hADSCs) from diabetes mellitus (DM) patients result in remarkable retention of stem cell activity due to diabetes-induced glucolipotoxicity. We explored...

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Detalles Bibliográficos
Autores principales: Xiao, Shune, Zhang, Dan, Liu, Zhiyuan, Jin, Wenhu, Huang, Guangtao, Wei, Zairong, Wang, Dali, Deng, Chengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202540/
https://www.ncbi.nlm.nih.gov/pubmed/32294623
http://dx.doi.org/10.18632/aging.103053