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Diabetes-induced glucolipotoxicity impairs wound healing ability of adipose-derived stem cells-through the miR-1248/CITED2/HIF-1α pathway
Despite being an attractive cell type for mesenchymal stem cell (MSC) transplantation therapy for wound healing, human adipose-derived stem cells (hADSCs) from diabetes mellitus (DM) patients result in remarkable retention of stem cell activity due to diabetes-induced glucolipotoxicity. We explored...
Autores principales: | Xiao, Shune, Zhang, Dan, Liu, Zhiyuan, Jin, Wenhu, Huang, Guangtao, Wei, Zairong, Wang, Dali, Deng, Chengliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202540/ https://www.ncbi.nlm.nih.gov/pubmed/32294623 http://dx.doi.org/10.18632/aging.103053 |
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