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PGC-1α activator ZLN005 promotes maturation of cardiomyocytes derived from human embryonic stem cells

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have great potential in biomedical applications. However, the immature state of cardiomyocytes obtained using existing protocols limits the application of hPSC-CMs. Unlike adult cardiac myocytes, hPSC-CMs generate ATP through an immature...

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Detalles Bibliográficos
Autores principales: Liu, Yanping, Bai, Huajun, Guo, Fengfeng, Thai, Phung N., Luo, Xiaoling, Zhang, Peng, Yang, Chunli, Feng, Xueqin, Zhu, Dan, Guo, Jun, Liang, Ping, Xu, Zhice, Yang, Huangtian, Lu, Xiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202542/
https://www.ncbi.nlm.nih.gov/pubmed/32343674
http://dx.doi.org/10.18632/aging.103088