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Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18

Intestinal epithelial cells (IECs) are at the forefront of host-pathogen interactions, coordinating a cascade of immune responses to protect against pathogens. Here we show that IEC-intrinsic vitamin A signaling restricts pathogen invasion early in the infection and subsequently activates immune cel...

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Detalles Bibliográficos
Autores principales: Iyer, Namrata, Grizotte-Lake, Mayara, Duncan, Kellyanne, Gordon, Sarah R., Palmer, Ana C. S., Calvin, Crystle, Zhong, Guo, Isoherranen, Nina, Vaishnava, Shipra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202665/
https://www.ncbi.nlm.nih.gov/pubmed/32330185
http://dx.doi.org/10.1371/journal.ppat.1008360