Cargando…
Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18
Intestinal epithelial cells (IECs) are at the forefront of host-pathogen interactions, coordinating a cascade of immune responses to protect against pathogens. Here we show that IEC-intrinsic vitamin A signaling restricts pathogen invasion early in the infection and subsequently activates immune cel...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202665/ https://www.ncbi.nlm.nih.gov/pubmed/32330185 http://dx.doi.org/10.1371/journal.ppat.1008360 |