Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

Mitochondria physically associate with the endoplasmic reticulum to coordinate interorganelle calcium transfer and regulate fundamental cellular processes, including inflammation. Deregulated endoplasmic reticulum–mitochondria cross-talk can occur in cystic fibrosis, contributing to hyperinflammatio...

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Detalles Bibliográficos
Autores principales: Rimessi, Alessandro, Pozzato, Chiara, Carparelli, Lorenzo, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Cigana, Cristina, Talarico, Anna, Wieckowski, Mariusz R., Ribeiro, Carla M. P., Trapella, Claudio, Rossi, Giacomo, Cabrini, Giulio, Bragonzi, Alessandra, Pinton, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202873/
https://www.ncbi.nlm.nih.gov/pubmed/32494695
http://dx.doi.org/10.1126/sciadv.aax9093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202873/
https://www.ncbi.nlm.nih.gov/pubmed/32494695
http://dx.doi.org/10.1126/sciadv.aax9093

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