Long non-coding RNA GRASLND enhances chondrogenesis via suppression of the interferon type II signaling pathway

The roles of long noncoding RNAs (lncRNAs) in musculoskeletal development, disease, and regeneration remain poorly understood. Here, we identified the novel lncRNA GRASLND (originally named RNF144A-AS1) as a regulator of mesenchymal stem cell (MSC) chondrogenesis. GRASLND, a primate-specific lncRNA,...

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Detalles Bibliográficos
Autores principales: Huynh, Nguyen PT, Gloss, Catherine C, Lorentz, Jeremiah, Tang, Ruhang, Brunger, Jonathan M, McAlinden, Audrey, Zhang, Bo, Guilak, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202894/
https://www.ncbi.nlm.nih.gov/pubmed/32202492
http://dx.doi.org/10.7554/eLife.49558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202894/
https://www.ncbi.nlm.nih.gov/pubmed/32202492
http://dx.doi.org/10.7554/eLife.49558

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